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. 2017 Jul 25;22(8):1243. doi: 10.3390/molecules22081243

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of 11 or cisplatin on mitochondrial membrane potential in HL-60 cells. HL-60 cells were stained with MitoCapture^TM reagent after the following treatments for 6 h (magnification, 200×): (a) control; (b) 10 µM of 11; and (c) 33 µM of cisplatin. Red fluorescence indicates accumulation of MitoCapture^TM dye in the mitochondria due to normal mitochondrial membrane potential. Green fluorescence indicates cytosolic localization of MitoCapture^TM dye in its monomeric form due to altered mitochondrial membrane potential.