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. 2017 Jul 4;22(7):1109. doi: 10.3390/molecules22071109

Table 1.

Cytotoxic effects of compounds 19 and cisplatin on A549, C6, and NIH/3T3 cells.

Compound IC50 Values for Cell Lines (mM) SI Values 1
NIH/3T3 A549 C6 A549 C6
1 0.308 ± 0.037 >1.234 0.128 ± 0.027 24.959 240.625
2 1.413 ± 0.094 >1.432 >1.432 98.673 98.673
3 1.369 ± 0.074 1.369 ± 0.058 0.507 ± 0.049 100 270.018
4 1.285 ± 0.090 >1.285 >1.285 100 100
5 >1.066 >1.066 >1.066 100 100
6 >1.211 >1.211 >1.211 100 100
7 0.100 ± 0.011 >1.166 >1.166 8.576 8.576
8 >1.104 0.125 ± 0.020 0.137 ± 0.015 883.200 805.839
9 0.888 ± 0.029 0.349 ± 0.046 0.157 ± 0.016 254.441 565.605
Cisplatin >1.166 0.140 ± 0.030 0.103 ± 0.026 1190 1617.476

1 SI values were calculated from the equation as follows: SI=IC50value for NIH/3T3 cell lineIC50value for A549 or C6 cell line ×100.