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Study design. Subjects entered the metabolic chamber at 0800 h and remained there until 1400 h, after which they were transported to the PET/CT suite. Blood was drawn before treatment (tx) at 0800 h and then just prior to 18F-FDG administration at 1300 h. The black bars above the diagrams refer to the 30-min still periods during which REE was measured. PK, pharmacokinetic.
