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. 2018 Jun 1;67(7):1003–1011. doi: 10.1099/jmm.0.000765

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© 2018 The Authors

This is an open access article under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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Fig. 1. — Genetic relationship of PBP1a, PBP2b and PBP2x amino acid sequences. (a–c) Pair-wise alignments generated by BioNumerics 7.6. showing the relatedness of pbp1a (a), pbp2b (b) and pbp2x (c) nucleotide sequences among penicillin-susceptible R6, multidrug-resistant 19F A026, Taiwan^19F-14, Hungary^19A-6 and 19A/19F isolates. (d) Amino acid substitution sites of PBP2b. The sequences were aligned according to the corresponding amino acid sequences of R6. PEN, penicillin; CTX, cefotaxime; S, susceptible; R, resistant.