Table 3.

The performance of all sub-models in external validation.

Model	LncRNA feature	Protein feature	AUC	ACC	REC	SPEC	PPV	F1 score	TP	FN	FP	TN
SVM	Kmer	Kmer	0.7351	0.5687	0.9629	0.1744	0.5384	0.6906	2628	101	2253	476
SVM	Kmer	AC	0.7172	0.5381	0.9728	0.1033	0.5203	0.6780	2655	74	2447	282
SVM	Kmer	PC-PseAAC-General	0.7326	0.6357	0.9278	0.3437	0.5857	0.7180	2532	197	1791	938
SVM	DAC	Kmer	0.7243	0.5122	0.9849	0.0395	0.5063	0.6688	2688	41	2621	108
SVM	DAC	AC	0.7495	0.5461	0.9589	0.1333	0.5252	0.6787	2617	112	2365	364
SVM	DAC	PC-PseAAC-General	0.7088	0.6416	0.8603	0.4228	0.5985	0.7059	2348	381	1575	1154
SVM	PC-PseDNC-General	Kmer	0.7446	0.5390	0.9703	0.1077	0.5209	0.6779	2648	81	2435	294
SVM	PC-PseDNC-General	AC	0.7340	0.5388	0.9681	0.1095	0.5208	0.6773	2642	87	2430	299
SVM	PC-PseDNC-General	PC-PseAAC-General	0.7433	0.6299	0.9234	0.3363	0.5818	0.7138	2520	209	1811	918
RF	Kmer	Kmer	0.8066	0.5344	0.9791	0.0897	0.5182	0.6777	2672	57	2484	245
RF	Kmer	AC	0.8089	0.5153	0.9893	0.0414	0.5079	0.6712	2700	29	2616	113
RF	Kmer	PC-PseAAC-General	0.8026	0.6227	0.9377	0.3078	0.5753	0.7131	2559	170	1889	840
RF	DAC	Kmer	0.7974	0.5732	0.9582	0.1883	0.5414	0.6918	2615	114	2215	514
RF	DAC	AC	0.7935	0.5472	0.9739	0.1205	0.5255	0.6826	2658	71	2400	329
RF	DAC	PC-PseAAC-General	0.7956	0.6143	0.9428	0.2858	0.5689	0.7096	2573	156	1949	780
RF	PC-PseDNC-General	Kmer	0.8106	0.5489	0.9721	0.1256	0.5264	0.6830	2653	76	2386	343
RF	PC-PseDNC-General	AC	0.8071	0.5164	0.9890	0.0439	0.5084	0.6716	2699	30	2609	120
RF	PC-PseDNC-General	PC-PseAAC-General	0.8036	0.6271	0.9369	0.3173	0.5785	0.7153	2557	172	1863	866
XGB	Kmer	Kmer	0.8032	0.6423	0.9391	0.3455	0.5893	0.7242	2563	166	1786	943
XGB	Kmer	AC	0.7930	0.6452	0.9292	0.3613	0.5926	0.7237	2536	193	1743	986
XGB	Kmer	PC-PseAAC-General	0.7971	0.6582	0.9270	0.3895	0.6029	0.7306	2530	199	1666	1063
XGB	DAC	Kmer	0.7938	0.6201	0.9483	0.2920	0.5725	0.7140	2588	141	1932	797
XGB	DAC	AC	0.8205	0.6311	0.9501	0.3122	0.5800	0.7203	2593	136	1877	852
XGB	DAC	PC-PseAAC-General	0.8046	0.6192	0.9468	0.2916	0.5720	0.7132	2584	145	1933	796
XGB	PC-PseDNC-General	Kmer	0.7875	0.6476	0.9380	0.3572	0.5934	0.7269	2560	169	1754	975
XGB	PC-PseDNC-General	AC	0.7776	0.6526	0.9201	0.3851	0.5994	0.7259	2511	218	1678	1051
XGB	PC-PseDNC-General	PC-PseAAC-General	0.7914	0.6575	0.9322	0.3829	0.6017	0.7313	2544	185	1684	1045