Figure 8.

Examples of new transcript variants formed by Alu insertion (images were prepared using UCSC table browser). Alu elements are marked by a red bar. (A) AluJo insertion into an intron of the gene ERBB3 may have created a shorter transcript. (B) Insertion of an AluSq2 element into the 3′UTR of the gene THUMPD3 may have generated two transcripts with shorter 3′UTR. (C) The longest transcript of the gene MMP19 may have formed by the insertion of an AluJb element just downstream of its 3′UTR. (D) Insertion of an AluSx1 element within the intron of the gene HSD11B1L may have created shorter transcript with new exon and 3′UTR.