Figure 6.

In vitro tumor cell proliferation inhibition evaluation. (a,b,c,d,e). Tumor cell proliferation inhibition by treating with the anti-HER2 antibodies T-mab, P-mab, combination of T-mab and P-mab (T-mab + P-mab), and MBS301, respectively, at a series of diluted concentrations from 100 to 0.0015 μg/ml on HER2+ cells BT474, MDA-MB-175VII, NCI-N87, SK-BR-3 and HCC1419. (F). The inhibition rates of the anti-HER2 antibodies on different HER2+ cancer cell lines that were calculated at the highest concentration of 100 μg/ml when a steady plateau was reached for each assay. *P < 0.0001 by one-way ANOVA analyses for the inhibition rate difference for the three cancer cell lines.