Table 1. Selected cytokine and chemokine levels in bronchoalveolar lavage fluid.
Cytokine | IL-6 | KC | ||
---|---|---|---|---|
Mouse Group | − NTHi | + NTHi* | − NTHi | + NTHi* |
CC-LR | 19.9 ± 1.6 | 131 ± 3.0 | 29.7 ± 8.9 | 126.7 ± 9.4 |
CC-LR/HIF-1αΔ/Δ | 2.09 ± 0.6 | 44.55 ± 12.9 | 16.98 ± 7.5 | 51.06 ± 10.8 |
CC-LR/HIF-1α Tg | 61.61 ± 9.2 | N/A | 33.7 ± 5.6 | N/A |
Abbreviations: NTHi, nontypeable Haemophilus influenza; IL-6, interleukin 6; KC, keratinocyte-derived chemokine, N/A, not applicable.
All data are the mean ± SEM and are expressed as pg/ml (n = 4).
*Bronchoalveolar lavage fluids were collected at the age of 14 weeks and the first day after 8th NTHi exposure.