Table 1.
Data in control Atg7f/f:apoeKO mice mice and Atg7cKO:apoeKO mice after 14-weeks of Western-diet load.
| Atg7f/f:apoeKO mice | Atg7cKO:apoeKO mice | P value | |
|---|---|---|---|
| Normal chow diet | |||
| Body weight (g) | 33.34 ± 1.27 (n = 10) | 31.92 ± 0.97 (n = 13) | 0.389 |
| Average food consumption (g/day) | 3.31 ± 0.02 (n = 10) | 3.22 ± 0.08 (n = 13) | 0.17 |
| Western diet | |||
| Body weight (g) | 34.89 ± 0.98 (n = 23) | 31.55 ± 0.56 (n = 34) | 0.005 |
| Average food consumption (g/day) | 3.04 ± 0.49 (n = 23) | 2.92 ± 0.39 (n = 34) | 0.33 |
| Mean systemic arterial pressure (mmHg) | 78.3 ± 1.6 (n = 21) | 77.0 ± 2.5(n = 33) | 0.73 |
| Total cholesterol (mg/dl) | 834.2 ± 52.1 (n = 23) | 568.3 ± 26.1 (n = 35) | 0.0048 |
| LDL cholesterol (mg/dl) | 173.8 ± 9.9 (n = 23) | 147.0 ± 9.7 (n = 35) | 0.058 |
| HDL cholesterol (mg/dl) | 15.2 ± 0.6 (n = 23) | 13.0 ± 0.5 (n = 35) | 0.0075 |
| Triglyceride (mg/dl) | 33.0 ± 2.7 (n = 23) | 22.7 ± 1.6 (n = 35) | 0.002 |
Blood samples were collected from control Atg7f/f:apoeKO mice and Atg7cKO:apoeKO mice fed a normal chow diet or a Western diet for 14 weeks. Each sample was obtained in the fasting state. Data are represented as mean ± SEM.