Table 2.
Antibacterial activity of designed peptides derived from LfcinB 17–31.
| Code | E. coli | S. aureus | |||
|---|---|---|---|---|---|
| ATCC 25922 | ATCC 25923 | ||||
| MIC | MBC | MIC | MBC | ||
| Lineal peptides | 200 | >200 | >200 | >200 | |
| >200 | >200 | >200 | >200 | ||
| 100 | 100 | >200 | >200 | ||
| 200 | >200 | >200 | >200 | ||
| 200 | 200 | >200 | >200 | ||
| 200 | >200 | - | - | ||
| 200 | 200 | >200 | >200 | ||
| 100 | 200 | >200 | >200 | ||
| 100 | 200 | 200 | 200 | ||
| 100 | 100 | >200 | >200 | ||
| >200 | >200 | >200 | >200 | ||
| - | - | >200 | >200 | ||
| Polyvalent peptides | - | - | 12.5 | 12.5 | |
| (LfcinB 21–25)Pal | 12.5 | 25 | - | - | |
| (LfcinB 20–25)4 | 6.25 | 12.5 | 25 | 25 | |
| Protein | BLF | >50 | >50 | >50 | >50 |
n = 2; Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) in μM.