Table 4.
Suggestions of biological activities for 6-hydroxyflavone at Pa > 79.2%—second analysis by PASS online tool.
| PA | PI | Activity |
|---|---|---|
| 0.957 | 0.003 | Agonist of membrane integrity |
| 0.949 | 0.002 | Chlordecone reductase inhibitor |
| 0.948 | 0.004 | HIF1A expression inhibitor |
| 0.945 | 0.004 | CYP2C12 substrate |
| 0.935 | 0.003 | Inhibitor of membrane permeability |
| 0.932 | 0.001 | Aryl alcohol dehydrogenase inhibitor (NADP+) |
| 0.932 | 0.001 | Inhibitor of 4-nitrophenol 2-monooxygenase |
| 0.929 | 0.003 | Inhibitor aldehyde oxidase |
| 0.924 | 0.002 | Inhibitor of p-benzoquinone reductase (NADPH) |
| 0.915 | 0.002 | Inhibitor colestanetriol 26-monooxygenase |
| 0.914 | 0.003 | Kinase inhibitor |
| 0.907 | 0.002 | Inhibitor 27-Hydroxycolesterol 7α-monooxygenase |
| 0.901 | 0.003 | Inhibitor 2-2-dehydropantoate reductase |
| 0.895 | 0.004 | Anaphylatoxin receptor antagonist |
| 0.894 | 0.002 | CYP1A inducer |
| 0.892 | 0.003 | Peroxidase inhibitor |
| 0.888 | 0.002 | Antimutagenic |
| 0.887 | 0.011 | Aspulvinone dimethylallyltransferase inhibitor |
| 0.884 | 0.002 | MAP kinase stimulant |
| 0.880 | 0.001 | Quercetin 2.3-dioxygenase inhibitor inhibitor |
| 0.875 | 0.006 | Anti-seborreic |
| 0.868 | 0.002 | CYP1A1 inducer |
| 0.852 | 0.007 | Enhances expression of TP53 |
| 0.851 | 0.005 | CYP1A substrate |
| 0.850 | 0.003 | Inhibitor of NADPH-ferrihemoprotein reductase |
| 0.850 | 0.003 | CYP2B5 substrate |
| 0.844 | 0.003 | Enhances expression of HMOX1 |
| 0.843 | 0.003 | CYP2A4 substrate |
| 0.843 | 0.004 | UGT1A9 substrate |
| 0.840 | 0.003 | Inhibitor of Pin1 |
| 0.840 | 0.004 | Vasoprotector |
| 0.841 | 0.005 | Expression of JAK2 inhibitor |
| 0.833 | 0.003 | Inhibitor of alcohol dehydrogenase (NADP+) |
| 0.829 | 0.002 | Inhibitor of leukotriene-B4 20-monooxygenase |
| 0.828 | 0.005 | Alkane 1-monooxygenase inhibitor |
| 0.822 | 0.005 | Inhibitor of oxidoreductase |
| 0.820 | 0.016 | Methylenetetrahydrofolate reductase inhibitor (NADPH) |
| 0.817 | 0.005 | Substrate of CYP1A1 |
| 0.815 | 0.003 | Inhibitor of β-carotene 15.15′-monooxygenase |
| 0.815 | 0.004 | Histidine kinase inhibitor |
| 0.809 | 0.002 | 2-Enoate reductase inhibitor |
| 0.809 | 0.013 | 5 Hydroxytryptamine release stimulant |
| 0.808 | 0.003 | Inhibitor of nitrite reductase [NAD (P) H] |
| 0.806 | 0.004 | UGT1A6 substrate |
| 0.805 | 0.017 | Mucous membrane protector |
| 0.802 | 0.016 | Gluconate 2-dehydrogenase inhibitor |
| 0.801 | 0.002 | Inhibitor of Glycerol dehydrogenase (NADP+) |
| 0.797 | 0.002 | CYP1A2 inducer |
| 0.797 | 0.003 | Inhibitor of histamine release |
Pa = (probability “to be active”), Pi = (probability “to be inactive”).