Skip to main content
. 2017 Jun 8;22(6):953. doi: 10.3390/molecules22060953

Table 1.

Synthesis of compound 1.

graphic file with name molecules-22-00953-i001.jpg

Entry Solvent Additive Time T (°C) Discoloration
1 H2O none 2 h 70 No
2 THF none 2 h reflux No
3 H2O TFA 10 mol % 1 h 70 No
4 THF TFA 10 mol % 20 min reflux Yes
5 H2O/THF TFA 10 mol % 20 min 70 Yes