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. 2017 Jun 2;22(6):924. doi: 10.3390/molecules22060924

Scheme 2.

Scheme 2

Synthesis of the GA amino acid derivatives 1232. Reagents and conditions: (a) K2CO3, alkyl halides, DMF, 24 h, 25 °C; (b) These compounds were synthesized by DCC mediated esterification of N-Boc protected amino acids followed by their deportation using TFA in dry DCM (for the amines) or by treating them with dry HCl gas in DCM (for the ammonium hydrochlorides).