Table 13.

Cytotoxicity (GI₅₀ values in μM) of 141–155 in a panel of various cancer cell lines.

Compound	A549	DU145	KB	Kbvin
GA	61.2 ± 2.33	64.9 ± 0.505	61.2 ± 0.118	62.3 ± 1.41
141	>70	>70	>70	>70
142	>70	>70	>70	>70
143	19.4 ± 0.909	19.3 ± 0.292	14.6 ± 0.448	14.9 ± 0.471
144	34.2 ± 1.88	28.9 ± 0.921	17.5 ± 0.927	18.6 ± 0.931
145	23.3 ± 0.304	21.7 ± 0.402	16.9 ± 0.501	19.2 ± 0.497
146	44.0 ± 0.057	45.5 ± 0.666	39.9 ± 0.618	47.6 ± 1.06
147	18.3 ± 0.373	17.4 ± 0.619	15.3 ± 0.469	19.5 ± 1.33
148	>70	>70	>70	>70
149	19.6 ± 1.60	22.0 ± 0.546	16.0 ± 0.368	17.0 ± 0.377
150	15.0 ± 0.689	15.0 ± 0.363	14.2 ± 0.670	13.7 ± 1.25
151	46.7 ± 1.90	46.2 ± 0.697	45.5 ± 1.04	46.9 ± 0.230
152	46.1 ± 0.653	45.2 ± 1.27	41.3 ± 0.346	44.2 ± 0.280
153	19.0 ± 1.13	22.5 ± 0.606	17.8 ± 0.193	16.6 ± 0.591
154	34.5 ± 0.187	39.5 ± 1.05	30.7 ± 0.480	27.3 ± 0.338
155	41.5 ± 1.83	43.2 ± 1.61	38.4 ± 1.15	38.5 ± 0.956