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Effect of different treatments of Serjania schiedeana on TNF-α concentration in joint and spleen of mice exposed to monoarthritis with kaolin/carrageenan (K/C). SeAcOEt = ethyl Acetate extract of S. schiedeana; F-14 = a fraction from the extract; ETP = epicatechin trimeric proanthocyanidin; MTX = methotrexate; MEL = meloxicam; VEH = negative control. Analysis of Student t test (n = 4; mean ± SD). * p < 0.05 compared with VEH.
