Table 7. Median and range values of IFN-γ as a potential host biomarker detected in overnight culture supernatant by WBA for the leprosy group and control groups.
Marker/M.leprae Antigens | MB | PB | post-MDT | HHC | EC | TB | |
---|---|---|---|---|---|---|---|
IFN-γ/LID-1 | Median | 44.56 | 68.76 | 73.51 | 49.04 | 25.9 | 53.46 |
Minimum | 0.93 | 1.78 | 14.27 | 1.12 | 22.18 | 14.41 | |
Maximum | 502.7 | 1079 | 981.3 | 2036 | 46.17 | 411.9 | |
IFN-γ/ML89 | Median | 23.7 | 36.72 | 60.95 | 48.36 | 22.18 | 49.33 |
Minimum | 0.75 | 1.29 | 10.76 | 0.89 | 17.31 | 14.38 | |
Maximum | 710.4 | 1155 | 1397 | 2441 | 51.63 | 371.4 | |
IFN-γ/ML2044 | Median | 37.33 | 76.14 | 29.57 | 38.26 | 20.38 | 35.3 |
Minimum | 0.78 | 1.78 | 10.45 | 0.89 | 16.45 | 16.05 | |
Maximum | 1150 | 1257 | 606.9 | 1118 | 42.44 | 388 | |
IFN-γ/ML2028 | Median | 29.73 | 33.19 | 25.75 | 26.83 | 18.61 | 32.5 |
Minimum | 0.75 | 1.29 | 10.45 | 0.85 | 14.35 | 14.15 | |
Maximum | 620.1 | 685.1 | 900.2 | 2758 | 47.79 | 380.6 |
Median levels of analytes (pg/ml) and ranges (minimum and maximum) showing accuracies at discriminating between leprosy and controls in overnight culture supernatants for all of the study participants.