Table 3.
Multivariable Survival Analysis for Patients Receiving Surgery, EBRT, or SBRT for Stage I SCLC
| Characteristic | Overall Survival, % | Adjusted Hazard Ratios | |||
|---|---|---|---|---|---|
| 2-Year | 3-Year | Hazard Ratio | 95% CI | P | |
| Mean Age | 1.02 | 1.01-1.03 | <.001 | ||
| Sex | |||||
| Male | 58 | 46 | 1.00 | ||
| Female | 64 | 53 | 0.84 | 0.76-0.92 | <.001 |
| Race | |||||
| Caucasian | 62 | 49 | 1.00 | ||
| African American | 65 | 57 | 0.89 | 0.73-1.08 | .23 |
| Other or not identified | 54 | 50 | 0.96 | 0.71-1.30 | .81 |
| Charlson—Deyo Score | |||||
| 0 | 62 | 50 | 1.00 | ||
| 1 | 63 | 51 | 1.12 | 1.00-1.25 | .05 |
| 2+ | 55 | 44 | 1.36 | 1.18-1.57 | <.001 |
| T Stage | |||||
| 1 | 65 | 53 | 1.00 | ||
| 2 | 57 | 45 | 1.14 | 1.02-1.26 | .02 |
| Facility Type | |||||
| Academic/research program | 64 | 52 | 1.00 | ||
| Community program | 61 | 50 | 1.03 | 0.92-1.16 | .30 |
| Chemotherapy | |||||
| Yes | 62 | 50 | 0.66 | 0.57-0.76 | <.001 |
| No | 58 | 47 | 1.00 | ||
| Unknown | 68 | 61 | 0.71 | 0.46-1.09 | .113 |
| Treatment Modality | |||||
| Surgery | 72 | 62 | 1.00 | ||
| EBRT | 56 | 44 | 1.99 | 1.74-2.28 | <.001 |
| SBRT | 56 | 40 | 1.67 | 1.32-2.10 | <.001 |
Abbreviations: EBRT = external beam radiation therapy; SBRT = stereotactic body radiation therapy; SCLC = small-cell lung cancer.