Table 3.

Decreased expression of genes from colonic biopsies in Crohn’s patients with loss of response to anti-TNFα therapy versus those who respond

Gene	Fold Change	P-value	Adjusted P-value*	Rank**
FAM151A	−5.18	0.005	0.17	1
CNTFR	−5.13	1.6 × 10−9	7.6 × 10−9	2
SULT2A1	−4.81	0.006	0.19	3
G6PC	−4.39	0.0004	0.05	4
CDHR1	−3.30	0.0001	0.03	5
TNC22	−2.96	0.0003	0.05	6
ESRRG	−2.40	0.0004	0.05	7
SLC25A34	−2.23	0.0004	0.05	8
FZD7	−2.14	9.1 × 10−5	0.03	9
MYOM3	−2.10	6.2 × 10−5	0.03	10

^*= Boneferroni corrected

^**= calculated by weighing of fold change and P-value