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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Dev Biol. 2018 Jul 5;441(1):191–203. doi: 10.1016/j.ydbio.2018.07.003

Figure 3. Constitutive activation of the Hh pathway in the palatal epithelium alters MEE cell fate without affecting periderm disappearance or actomyosin-driven cell movement.

Figure 3.

(A-H) Immunofluorescence of active caspase 3 (Casp3, green), phospho-histone H3 (pH3, red), SSEA1 (green), and non-muscle myosin heavy chain IIA (NMHCIIA, red) in frontal sections of E14.5 control and K14-Cre;R26SmoM2 palatal shelves. Arrows indicate positive signal; arrowheads indicate absence of signal. White dotted lines indicate the location of the MEE. Scale bars: 50 μm.