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. Author manuscript; available in PMC: 2019 Aug 22.
Published in final edited form as: Neuron. 2018 Aug 9;99(4):665–679.e5. doi: 10.1016/j.neuron.2018.07.020

Figure 2. Microtubule-targeting enhances the performance of AKAR sensors.

Figure 2.

(A) Schematic of tAKAR variants.

(B) Representative basal fluorescence intensity and Δlifetime/lifetime0 images in the apical dendrite of CA1 neurons with the indicated simulations. LT: lifetime.

(C, D) Representative timecourse traces (C) and amplitudes (D) of Δlifetime/lifetime0 of tAKARs. n = 6 – 7 neurons for all sensors.

Error bars are s.e.m.

See also Figure S3.