. Author manuscript; available in PMC: 2019 Sep 1.

Published in final edited form as: Bioorg Med Chem Lett. 2018 Apr 7;28(16):2697–2700. doi: 10.1016/j.bmcl.2018.04.003

Table 2.

Radio-ligand binding assay screen for compds 3 and 11 in cloned receptors and transporters. Both 3 and 11 are inactive in all assays.

Adrenoreceptors	α_1A, α_1B, α_1Δ, α_2A, β₁, β₂, β₃
Biogenic amine transporters	DAT, NET, SERT
Dopamine receptors	D₁, D₂, D₃, D₄, D₅
Opioid receptors	DOR, KOR, MOR
Histamine receptors	H₁, H₂, H₃, H₄
Muscarinic receptors	M₁, M₂, M₃, M₄, MS
Serotonin receptors	5-HT_1A, 5-HT_1B, 5-HT_1D, 5-HT_1E, 5-HT_2A, 5-HT_2B, 5-HT_2C, 5-HT₃, 5-HT_5A, 5-HT₆, 5-HT₇
Sigma receptors	rSigma₁, rSigma₂