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. 2018 Sep 24;16(9):e2005004. doi: 10.1371/journal.pbio.2005004

Fig 7. Midgut-derived NPF controls mating-induced GSC proliferation.

Fig 7

A model illustrating the mechanism based on this study. SP signaling induces NPF release from midgut EECs. NPF positively controls pMad expression in GSCs to induce GSC proliferation via ovarian NPFR. BMP, bone morphogenetic protein; EEC, enteroendocrine cell; GSC, germline stem cell; NPF, neuropeptide F; NPFR, neuropeptide F receptor; OSC, ovarian somatic cell; pMad, phosphorylated Mad; SP, sex peptide.