Table 2. Sensitivity of C-Tb versus TST (top) and QFT (bottom) in microbiologically confirmed active TB cases.
| All | HIV-uninfected | HIV co-infected |
|
|---|---|---|---|
| C-Tb versus TST | |||
| N | 75 | 41 | 34 |
| C-Tb pos. (%) | 72.0 (60.9–81.0) |
75.6 (60.5–86.4) |
67.7 (50.8–81.0) |
| TST pos. (%) | 74.7 (63.7–83.2) |
73.2 (57.9–84.4) |
76.5 (59.8–87.8) |
| p-value* | 0.8026 | 1.0000 | 0.3711 |
| C-Tb versus QFT | |||
| N | 70 | 38† | 32‡ |
| C-Tb pos. (%) | 70.0 (58.4–79.5) |
73.7 (57.8–85.2) |
65.6 (48.2–79.7) |
| QFT pos. (%) | 58.6 (46.9–69.4) |
68.4 (52.5–81.0) |
46.9 (30.9–63.6) |
| p-value* | 0.1175 | 0.7518 | 0.1138 |
Data are presented as % (95% CI). Cut-point for TST was 5 mm in HIV-infected individuals and 15 mm in HIV-uninfected.
*McNemar’s test. In an intention to diagnose principle, QFT indeterminate results were included as negative.
†3 missing QFT. 5/5 QFT indeterminate results were C-Tb positives.
‡2 missing QFT. 5/9 QFT indeterminate results were C-Tb positives.