Table 1.
Population differences by era
| Total N=2896 |
Era 1 (2002 – 2006) N=649 (22.4%) |
Era 2 (2007 – 2011) N=1028 (35.5%) |
Era 3 (2012 – 2016) N=1219 (42.1%) |
p–valuea | |||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|||||||||
| Age | |||||||||
| <1 year | 896 | (30.9%) | 216 | (33.3%) | 328 | (31.9%) | 352 | (28.9%) | 0.458 |
| 1–5 years | 688 | (23.8%) | 152 | (23.4%) | 239 | (23.2%) | 297 | (24.4%) | |
| 6–10 years | 407 | (14.1%) | 94 | (14.5%) | 131 | (12.7%) | 182 | (14.9%) | |
| 11–17 years | 829 | (28.6%) | 174 | (26.8%) | 302 | (29.4%) | 353 | (29.%) | |
| 18–21 years | 76 | (2.6%) | 13 | (2.%) | 28 | (2.7%) | 35 | (2.9%) | |
| Diagnosis | |||||||||
| Cardiomyopathy | 1330 | (46.5%) | 284 | (44.4%) | 496 | (48.6%) | 550 | (45.7%) | 0.2 |
| Congenital Heart Disease | 1373 | (48.%) | 313 | (48.9%) | 466 | (45.7%) | 594 | (49.4%) | |
| Retransplant | 160 | (5.6%) | 43 | (6.7%) | 58 | (5.7%) | 59 | (4.9%) | |
| Race | |||||||||
| Caucasian | 1701 | (58.7%) | 381 | (58.7%) | 622 | (60.5%) | 698 | (57.3%) | 0.013 |
| African-American | 535 | (18.5%) | 143 | (22.%) | 184 | (17.9%) | 208 | (17.1%) | |
| Hispanic | 493 | (17.%) | 94 | (14.5%) | 162 | (15.8%) | 237 | (19.4%) | |
| Other | 167 | (5.8%) | 31 | (4.8%) | 60 | (5.8%) | 76 | (6.2%) | |
| Male Gender | 1585 | (54.7%) | 346 | (53.3%) | 556 | (54.1%) | 683 | (56.%) | 0.465 |
| Blood Type | |||||||||
| O | 1310 | (45.2%) | 286 | (44.1%) | 469 | (45.6%) | 555 | (45.5%) | 0.619 |
| A | 1087 | (37.5%) | 260 | (40.1%) | 379 | (36.9%) | 448 | (36.8%) | |
| B | 376 | (13.%) | 74 | (11.4%) | 133 | (12.9%) | 169 | (13.9%) | |
| AB | 123 | (4.2%) | 29 | (4.5%) | 47 | (4.6%) | 47 | (3.9%) | |
| Status at Transplant | |||||||||
| 1A | 2395 | (82.7%) | 483 | (74.4%) | 875 | (85.1%) | 1037 | (85.1%) | <0.001 |
| 1B | 320 | (11.%) | 80 | (12.3%) | 98 | (9.5%) | 142 | (11.6%) | |
| 2 | 181 | (6.3%) | 86 | (13.3%) | 55 | (5.4%) | 40 | (3.3%) | |
| ECMO at Transplant | 158 | (5.5%) | 59 | (9.1%) | 55 | (5.4%) | 44 | (3.6%) | <0.001 |
| VAD at Transplant | 493 | (17.%) | 46 | (7.1%) | 176 | (17.1%) | 271 | (22.2%) | <0.001 |
| Ventilator at Transplant | 493 | (17.%) | 129 | (19.9%) | 177 | (17.2%) | 187 | (15.3%) | 0.045 |
| Inotropes at Transplant | 1438 | (49.7%) | 297 | (45.8%) | 513 | (49.9%) | 628 | (51.5%) | 0.059 |
| Post-transplant iNO | 1452 | (50.2%) | 217 | (33.4%) | 494 | (48.1%) | 741 | (61.1%) | <0.001 |
| Total Length of Stay (Days) | 50 | (20–98) | 41 | (18–77) | 52 | (23–97) | 54 | (20–111) | <0.001 |
| Pre-transplant Length of Stay (Days) | 23 | (1–62) | 16 | (1–41) | 24 | (1–63) | 26 | (1–77) | <0.001 |
| Post-transplant Length of Stay (Days) | 18 | (12–32) | 18 | (10–31) | 18 | (12–33) | 19 | (12–33) | 0.016 |
| Post-Transplant ICU Days | 9 | (4–20) | 8 | (4–18) | 9 | (5–21) | 9 | (5–21) | 0.103 |
| Post-Transplant Days on Ventilator | 2 | (1–8) | 3 | (1–11.75) | 2 | (1–8) | 2 | (1–7) | <0.001 |
| Post-Transplant Complications | |||||||||
| Dialysis | 161 | (5.6%) | 48 | (7.4%) | 49 | (4.8%) | 64 | (5.3%) | 0.063 |
| Rejection Prior to Discharge | 360 | (13.6%) | 74 | (18.4%) | 139 | (13.5%) | 147 | (12.1%) | 0.006 |
| Stroke | 99 | (3.4%) | 18 | (2.8%) | 37 | (3.6%) | 44 | (3.6%) | 0.585 |
| Chylothorax | 147 | (5.1%) | 12 | (1.8%) | 64 | (6.2%) | 71 | (5.8%) | <0.001 |
| Cardiac Reoperation | 188 | (8.3%) | 50 | (7.8%) | 83 | (9.%) | 55 | (7.9%) | 0.63 |
a
p-values from the chi square test for categorical and Kruskal Wallis test for continuous variables