Table 2.
Era 1 (2002 – 2006) N=649 (22.4%) |
Era 2 (2007 – 2011) N=1028 (35.5%) |
Era 3 (2012 – 2016) N=1219 (42.1%) |
p-valuea | ||||||
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Overall | Era 1 vs. Era 2 | Era 2 vs. Era 3 | |||||||
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Unadjusted costs | |||||||||
Total cost | $680,831 | ($587,849– $788,521) | $730,861 | ($636,746– $838,885) | $670,273 | $587,527– $764,673) | 0.12 | 0.170 | 0.048 |
Pre-transplant costs | $182,311 | ($154,509– $215,117) | $280,286 | ($239,387– $328,173) | $279,555 | ($240,160– $325,412) | <0.001 | < 0.001 | 0.953 |
Post-transplant costs | $476,947 | ($407,388– $558,383) | $429,596 | ($370,058– $498,711) | $385,713 | ($334,151– $445,231) | <0.001 | 0.043 | 0.014 |
Adjusted costsb | |||||||||
Total cost | $913,390 | ($604,342– $1,380,480) | $906,454 | ($599,850– $1,369,776) | $767,221 | ($508,211– $1,158,237) | <0.001 | 0.899 | <0.001 |
Pre-transplant costs | $343,692 | ($270,794– $436,214) | $435,554 | ($344,417– $550,805) | $353,364 | ($281,608– $443,404) | <0.001 | <0.001 | < 0.001 |
Post-transplant costs | $586,298 | ($385,560– $891,550) | $586,133 | ($385,650– $890,837) | $508,719 | ($334,998– $772,526) | 0.003 | 0. 0.996 | 0.002 |
p-values from generalized linear mixed models
Cost expressed as least squares mean (Lower and Upper 95% confidence interval), inflated to 2016 dollars