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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Transplantation. 2018 Oct;102(10):1762–1767. doi: 10.1097/TP.0000000000002202

Table 2.

Unadjusted and adjusted hospitalization costs based on era

Era 1 (2002 – 2006)
N=649 (22.4%)
Era 2 (2007 – 2011)
N=1028 (35.5%)
Era 3 (2012 – 2016)
N=1219 (42.1%)
p-valuea

Overall Era 1 vs. Era 2 Era 2 vs. Era 3

Unadjusted costs
  Total cost $680,831 ($587,849– $788,521) $730,861 ($636,746– $838,885) $670,273 $587,527– $764,673) 0.12 0.170 0.048
  Pre-transplant costs $182,311 ($154,509– $215,117) $280,286 ($239,387– $328,173) $279,555 ($240,160– $325,412) <0.001 < 0.001 0.953
  Post-transplant costs $476,947 ($407,388– $558,383) $429,596 ($370,058– $498,711) $385,713 ($334,151– $445,231) <0.001 0.043 0.014
Adjusted costsb
  Total cost $913,390 ($604,342– $1,380,480) $906,454 ($599,850– $1,369,776) $767,221 ($508,211– $1,158,237) <0.001 0.899 <0.001
  Pre-transplant costs $343,692 ($270,794– $436,214) $435,554 ($344,417– $550,805) $353,364 ($281,608– $443,404) <0.001 <0.001 < 0.001
  Post-transplant costs $586,298 ($385,560– $891,550) $586,133 ($385,650– $890,837) $508,719 ($334,998– $772,526) 0.003 0. 0.996 0.002
a

p-values from generalized linear mixed models

b

Cost expressed as least squares mean (Lower and Upper 95% confidence interval), inflated to 2016 dollars