Table 3.

Predictors of Secondary Physical Outcomes from Repeated Measures Logistic/Negative Binomial Regression Models (n=245). Rate ratios or odds ratios greater than 1 are in bold.

	Number of health-related worries (count of 0 to 4)		Unable to do some physically activities as well since donation		Still not physically back to normal		Recovered slower or much slower than expected (2 or lower on scale of 1-much slower than expected to 3-as expected to 5-much faster)		Current donation-related medical problems		Donation was physically stressful (2 or lower on scale of 1-very stressful to 4-not at all stressful)
Predictors a	Rate Ratio (95% CI)	P-value	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Post-donation time point		0.003		<0.001		<0.001		0.005		0.45		0.22
3M vs. 2Y	1.31 (1.02, 1.68)	0.04	11.05 (6.37, 19.15)	<0.001	12.20 (5.41, 27.47)	<0.001	1.76 (1.27, 2.45)	<0.001	0.84 (0.52, 1.35)	0.48	1.45 (0.95, 2.20)	0.08
6M vs. 2Y	1.22 (0.96, 1.56)	0.12	3.66 (2.09, 6.40)	<0.001	4.96 (2.13, 11.54)	<0.001	1.19 (0.86, 1.64)	0.30	1.13 (0.73, 1.75)	0.59	1.22 (0.83, 1.78)	0.31
1Y vs. 2Y	0.90 (0.70, 1.17)	0.47	1.63 (0.97, 2.73)	0.051	1.98 (0.85, 4.63)	0.10	1.28 (0.94, 1.75)	0.12	0.94 (0.63, 1.39)	0.75	1.45 (0.97, 2.17)	0.07
Donor recipient relationship (ref=other biological or non-biological relative)												0.01
First degree relative											2.30 (1.32, 4.01)	0.003
Spouse/partner											4.60 (1.53, 13.84)	0.02
Unrelated											1.75 (0.86, 3.56)	0.12
Recipient death (time dependent)					3.55 (1.88, 6.68)	0.01					2.15 (1.05, 4.40)	0.04
Female vs. Male	1.39 (1.03, 1.87)	0.03					2.15 (1.28, 3.60)	0.003
Age at donation (per 10yrs increase)	0.81 (0.70, 0.94)	0.004
BMI at donation				0.051
25.0–29.9 vs. < 24.9			1.82 (1.12, 2.98)	0.017
>= 30 vs. < 24.9			1.20 (0.62, 2.32)	0.60
Length of hospital stay (per day)	1.13 (1.07, 1.20)	0.002	1.32 (1.15, 1.52)	<0.001	1.63 (1.39, 1.92)	<0.001	1.31 (1.10, 1.55)	0.005			1.16 (1.01, 1.32)	0.02
Hospitalized during the first month post-donation											3.25 (1.34, 7.90)	0.01
Had post-operative complications during the first month post-donation									2.33 (1.32, 4.14)	0.01
Pre-donation predictors
MCS pre-donation (per 10 increase on scale 1 to 100)	0.79 (0.67, 0.93)	0.01			0.72 (0.54, 0.95)	0.049					0.41 (0.27, 0.60)	<0.001
Ambivalence to donate (scale of 0-no ambivalence to 7-ambivalence)	1.17 (1.06, 1.28)	0.003									1.23 (1.05, 1.45)	0.01
Anticipated long-term health effects from donation	2.00 (1.48, 2.70)	<0.001									2.03 (1.26, 3.25)	0.004
Black sheep donor			1.73 (1.06, 2.80)	0.03
Anyone discouraged donor to donate									1.89 (1.17, 3.05)	0.01
Household income (per $10,000 increase)b							1.06 (1.00, 1.12)	0.04

OR, odds ratio; CI, confidence interval; BMI, body mass index; MCS, mental component summary.

^aVariables tested but not significant: donor demographics (race/ethnicity, education, marital status), clinical characteristics (hospitalized within 1st month post-donation, donation complications within 1st month), Simmons psychosocial background (donation history), Simmons donation decision-making items (other possible donors, anyone encouraged donor to donate, anticipated feeling life would be more worthwhile after donation), Simmons strength of motivation to donate, Patient Health Questionnaire-9 (PHQ-9)– depression score and Short Form-36 Physical Component Summary

^bIn the level of abdominal/back pain model where household income was significant, adjusting for household size didn’t change results and household size was not statistically significant.