Table 3.
Cox regression analysis for mortality rate following OLT.
| Characteristic | Model 1 | Model 2 | Model 3 |
|---|---|---|---|
| Age (per 5 yrs) | 1.16 | 1.16 | 1.19 |
| AFP at OLT (per 1,000 ng/mL) | 1.12 | 1.00 | 1.11 |
| AFP: rate of increase | -- | 3.42 | 1.19 |
| Sex = female | 1.45 | 1.59 | 1.51 |
| MELD at OLT | 1.03 | 1.03 | 1.02 |
| Difference in MELD(exception – lab) | 0.97 | 0.99 | 0.96 |
| Tumor size: initial presentation | 1.07 | -- | 1.06 |
| Tumor number: initial presentation | 1.26 | -- | 1.28 |
| Tumor size: explant pathology | -- | 1.19 | -- |
| Tumor number: explant pathology | -- | 1.09 | 1.28 |
| Progression (tumor size increase) | 1.47 | -- | 1.47 |
| Progression (tumor number increase) | 1.41 | -- | 1.41 |
| Time from initial presentation to OLT | 1.01 | 1.01 | 1.01 |
| Treatment (vs. no treatment) | |||
| RFA | -- | -- | -- |
| TACE | -- | -- | -- |
| RFA and TACE | -- | -- | -- |
| Calendar year of diagnosis (per year) | -- | 1.01 | 1.05 |
| Microvascular invasion | -- | 1.51 | -- |
Values presented for each model are hazard ratios (HR), with bold indicating significant (p<0.05) and underlined indicating “near-significant” (0.05 < p < 0.10)