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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: J Invest Dermatol. 2018 Mar 30;138(10):2253–2263. doi: 10.1016/j.jid.2018.03.1521

Figure 2. MiR-31 conditional deletion delays skin wound healing.

Figure 2.

(a) qRT-PCR for miR-31 in epidermis, duodenum and liver of miR-31 cKO and control. (b) Representative images of 1×1.5 cm2 skin wounds on miR-31 cKO and control mice on PWD 0 and 20. (c) Representative images and quantification of wound sizes in cKO and control mice on PWD 0, 2, 4, 6 and 8 after 6mm injury. (d) Schematics showing wound tissue sample collection. Histology and quantification of newly formed epidermis in miR-31 cKO and control wounds on PWD 6. Scale bar: 50 μm. (e,f,g) Immunostaining for keratins K17 (e) and K6 (f) and their quantification (g) in miR-31 cKO and control wounds on PWD 6. *p<0.05; **p <0.01; n ≥ 3 biological replicates for a-g.