Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 22;16:32–38. doi: 10.1016/j.bbrep.2018.09.003

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 4 — Effects of cyclic stretch on F-actin formation and expression of contractile proteins. (A) Representative 3-D immunofluorescence images of ASM cells cultured within gels with or without cyclic stretch. Reconstructed Z-stack confocal images of collagen gel constructs stained with α-smooth muscle actin (α-SMA), F-actin, DAPI, and merged images. Arrow indicates stretch direction. Effects of cyclic stretch on mRNA expression of α-SMA (ACTA2) (B), calponin (CNN1) (C), myosin heavy chain 11 (MYH11) (D), and transgelin (TAGLN) (E). Cyclic stretch was started 24 h after tissue fabrication and then applied for 48 h. Data are mean ± SD (n = 6). *Significantly different (P < 0.05) vs. the static condition.