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Proposed mechanisms of enhanced IL-10 production during MDR-bacterial infections and antibiotic treatment. The increased IL-10 production during MDR-bacteria can possibly be a consequence of (A) an improved ability of bacteria to synthesize polysaccharide capsule or (B) modifications in LPS. (C) Clarithromycin and probably other antibiotics promote the recruitment of myeloid suppressor cells and IL-10 production.
