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. 2018 Sep 18;9:418. doi: 10.3389/fpsyt.2018.00418

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Copyright © 2018 Bishop, Lee, Mills, Thuras, Eum, Clancy, Erbes, Polusny, Lamberty and Lim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SLC6A4 gene 5'UTR promoter region for DNA methylation detection. Three sets of primers were designed to cover the following: 1) the CpG island (SLC6A4_FR04; chr17: 28562752-28562954), 2) the CpG island shore (SLC6A4_FR05; chr17: 28563021-28563280), and 3) the SLC6A4 upstream region containing a short interspersed nuclear element (AluJb) located between the SLC6A4-5HTTLPR and the CpG island (SLC6A4_FR06; chr17: 28563438-28563675). Primer binding locations are indicated by arrows. All detected CpG sites are boxed and in bold font. The AluJb region is indicated by underlined and italicized font. Coordinates for the SLC6A4 gene region are based on Human Genome Build 37 (Human GRCh37/hg19).