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. 2018 Jul 6;38(4):BSR20180730. doi: 10.1042/BSR20180730

Figure 1. Paternal methyl donor depletion leads to increased anxiety-like behavior in F1 offspring.

Figure 1

(A) In the OFT, progeny of LR fathers that were fed a F1-DEP displayed increased anxiety-like behavior (diminished time in the center of the open field) compared with controls (F1-CON). No differences in time spent in the periphery or corners. (B) Paternal diet did not influence total activity in the OFT. (C,D) In the EPM, paternal methyl donor diet content did not affect time spent in the any zone within EPM or total exploratory activity. Data represent mean ± S.E.M.; * indicates P-value <0.05.