Table 2.
Means (standard deviations) for baseline tasks grouped by variant (N = 36)
| Task | lvPPA | nfvPA | svPPA | F (2, 33) | P value |
|---|---|---|---|---|---|
| Letter fluency (sum of words generated in one minute each for F, A, and S) | 16.00 (10.16) | 10.21 (5.85) | 18.50 (14.95) | 2.025 | .149 |
| Semantic fluency (sum of words generated in one minute each for fruits, animals, and vegetables) | 18.00 (12.00) | 12.08 (8.38) | 7.33 (5.52) | 3.416 | .046 |
| Object naming (BNT, 30 total) | 18.18 (10.26) | 17.54 (9.81) | 2.90 (3.04) | 10.672 | .000 |
| Action naming (HANA, 35 total) | 18.73 (10.66) | 17.54 (10.33) | 6.67 (7.11) | 4.584 | .018 |
| Digit span forward (9 total) | 3.42 (1.59) | 3.82 (1.67) | 5.60 (2.17) | 4.481 | .019 |
| Digit span backward (9 total) | 2.29 (0.92) | 2.32 (1.55) | 3.70 (2.52) | 2.367 | .109 |
| Spatial span forward (9 total) [44] | 3.65 (0.97) | 3.12 (1.80) | 3.61 (2.23) | 0.342 | .713 |
| Spatial span backward (9 total) | 3.15 (1.25) | 2.96 (1.66) | 3.50 (2.28) | 0.253 | .778 |
| JHU Sentence anagrams (10 total) | 7.00 (2.49) | 4.54 (3.67) | 5.56 (4.39) | 1.338 | .278 |
| Object semantics (PPT, 15 total) | 13.82 (2.44) | 13.75 (2.63) | 12.30 (2.06) | 1.323 | .281 |
| Action semantics (KD, 15 total) | 12.82 (2.64) | 12.83 (2.73) | 10.67 (3.39) | 1.798 | .184 |
| Sentence repetition (NACC, 37 words total) | 26.45 (7.13) | 21.60 (11.84) | 30.80 (6.83) | 2.707 | .084 |
| Syntactic comprehension (SOAP, 40 total) | 28.44 (6.11) | 25.55 (7.61) | 28.63 (8.78) | 0.526 | .597 |
| Verbal learning (RAVLT Delayed Recall, 15 total) | 5.67 (3.14) | 4.20 (2.28) | 4.25 (2.06) | 0.544 | .594 |
| Spelling words (JHU, % correct) | 81.35 (21.16) | 84.45 (15.12) | 87.12 (14.4) | 0.274 | .762 |
| Spelling nonwords (JHU, % correct) | 76.69 (16.54) | 59.04 (20.17) | 84.52 (20.42) | 4.014 | .031 |
Abbreviations: lvPPA, logopenic variant primary progressive aphasia; nfvPPA, nonfluent/agrammatic primary progressive aphasia; svPPA, semantic variant primary progressive aphasia; BNT, Boston Naming Test; HANA, Hopkins Assessment for Naming Actions; JHU, Johns Hopkins University; PPT, Pyramids and Palm Trees; KD, Kissing and Dancing; NACC, National Alzheimer's Coordinating Center; SOAP, Subject-relative, Object-relative, Active, and Passive; RAVLT, Rey Auditory Verbal Learning Test.