Table 1.
Amino Acid Residues at Equivalent Positions of 18 and 24 in Human, Carp and Zebrafish Granulins
| Residue 18 | Residue 24 | |
|---|---|---|
| Ala | ||
| Val | hF | |
| Leu | Grn1,AaG,AaD,AbF,AbH | |
| Ile | cGrn1,AbE | |
| Met | ||
| Cys | ||
| Phe | AbD | AaH |
| Trp | hA,hC,hF,cGrn1,Grn1,Grn2,AaA,AaB,AaC,AaE,AaF,AbA,AbB,AbC,AbD,AbE,AbG,AbI | |
| Gly | ||
| Pro | AaE | |
| Ser | ||
| Thr | AaD | |
| Tyr | hB,AaG,AbF,AbH | |
| Asn | ||
| Gln | hC,AaF,AaH,AbG | |
| Asp | ||
| Glu | hB | |
| Lys | AaA,AaB,AaC,AbA,AbB,AbC | |
| Arg | hA,Grn2,AbI | |
| His |
Note: cGrn1 and hA, hC, hF indicate carp granulin‐1 and human granulins A, C and F, respectively. Other GEMs are named according to the conventions used in this work (see Fig. 1), for example, AaE—GEM “E” from zebrafish progranluin Aa and AbB—GEM B from zebrafish progranulin Ab, etc.