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(A) Plasma blank, (B–E) QC samples spiked with paracetamol at (B) 0.125 mg/l (LLOQ), (C) 0.25 mg/l, (D) 5 mg/l and (E) 30 mg/l. Extracted ion chromatograms of paracetamol-D4 represented post-extraction concentration of 3.8 mg/l.
LLOQ: Lower limit of quantitation; QC: Quality control.
