Figure 1. . Transmission electron microscopy of the distribution of DNA and nuclear morphology during mitosis in trypanosomatids.

(A) Immunodetection of DNA in Strigomonas culicis. During mitosis, the chromatin and also the nucleolus are more dispersed. The arrow indicated the chromatin associated with the envelope. Reproduced with permission from [5]. (B) The mitotic spindle is seen throughout T. cruzi nucleus. Reproduced with permission from [6]. (C – G) Different stages of mitosis in Trypanosoma brucei, showing the chromatin extending through the nucleus, the initial formation of central constriction and the chromatin localization at the opposite poles. Kinetochores are represented by open brackets. Reproduced with permission from Chromosoma (2000) [7]. (H) The mitotic spindle present during the central constriction of the nucleus. Reproduced with permission from Chromosoma (1980) [6]. (I) Late mitosis when the nucleus is divided into two. The final connection between the nuclei can be observed (arrow).

Reproduced with permission from Chromosoma (2000) [7].