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. 2018 Jul 20;33(10):1011–1020. doi: 10.1007/s10654-018-0425-5

Table 4.

Risks of adverse neurodevelopmental outcome by early and late neonatal moderate hypoglycemia

Early hypoglycemia < 6 h N = 383 Late hypoglycemia > 6 h N = 1013
Crude Adjusteda Crude Adjusteda
Odds ratio 95% CI Odds ratio 95% CI Odds ratio 95% CI Odds ratio 95% CI
Any neurological or neurodevelopmental outcome 2.22 1.50–3.28 1.94 1.30–2.89 1.33 0.98–1.80 1.29 0.95–1.76
Any developmental delay 4.10 2.18–7.72 3.01 1.57–5.79 2.61 1.61–4.24 2.33 1.42–3.82
Motor developmental delay 2.75 1.02–7.40 2.34 0.86–6.41 2.08 1.03–4.19 1.93 0.95–3.92
Cognitive developmental delay 5.30 2.35–11.98 3.17 1.35–7.43 2.99 1.54–5.82 2.54 1.29–5.01

Congenital malformations, inborn errors of metabolism, and maternal diabetes are excluded

aAdjusted for mode of delivery, birth weight for gestational age, gestational age, sex, Apgar score and birth year