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. 2018 Jul 20;33(10):1011–1020. doi: 10.1007/s10654-018-0425-5

Table 5.

Risks of adverse neurological outcome by birth weight groups

Small for gestational age n = 5 675 Appropriate for gestational age n = 84 722 Large for gestational age n = 10 688
Number Rate/1000 live born OR 95% CI Number Rate/1000 live born OR 95% CI Number Rate/1000 live born OR 95% CI
Any neurological or neurodevelopmental outcome 225 39.6 2815 33.2 331 31.0
 No hypoglycemia 203 1.00 Reference 2769 1.00 Reference 322 1.00 Reference
 Hypoglycemia 22 2.10 1.33–3.32 46 1.52 1.13–2.05 9 0.95 0.50–1.79
Any developmental delay 58 10.2 549 6.48 68 6.36
 No hypoglycemia 52 1.00 Reference 529 1.00 Reference 65 1.00 Reference
 Hypoglycemia 6 2.18 0.93–5.11 20 3.45 2.20–5.41 3 1.92 0.70–5.29
Motor developmental delay 33 5.81 317 3.74 43 4.02
 No hypoglycemia 30 1.00 Reference 309 1.00 Reference 42 1.00 Reference
 Hypoglycemia 3 1.87 0.57–6.17 8 2.34 1.16–4.73 1 1.47 0.35–6.07
Cognitive developmental delay 29 5.11 256 3.02 29 2.71
 No hypoglycemia 26 1.00 Reference 244 1.00 Reference 27 1.00 Reference
 Hypoglycemia 3 2.16 0.65–7.15 12 4.46 2.49–8.00 2 2.34 0.55–9.87

Congenital malformations, inborn errors of metabolism, and maternal diabetes are excluded