Table 1.
Baseline characteristics of study sample and first CVD event during 10-year follow-up by age at clinical assessment (n = 11110)
| Characteristic | Age 50a | Age 60a |
|---|---|---|
| Number of participants | 7552 (68.0%)b | 5360 (48.2%)b |
| Systolic blood pressure, mmHg, median (IQR) | 125 (115, 140) | 136 (122, 150) |
| Total serum cholesterol, mmol/L, median (IQR) | 5.64 (5.00, 6.38)c | 5.96 (5.29, 6.70)d |
| Anti-hypertensive medication | 811 (10.7) | 1214 (22.7) |
| Current smoker | 1851 (24.5) | 1007 (18.8) |
| Diabetes mellitus | 66 (0.9) | 138 (2.6) |
| Body mass index, kg/m2, median (IQR) | 24.7 (22.7, 27.6) | 25.9 (23.5, 28.9) |
| Parity | ||
| 1 | 2926 (38.7) | 1678 (31.3) |
| 2 | 3394 (44.9) | 2646 (49.4%) |
| 3 | 981 (13.0) | 833 (15.5) |
| ≥ 4 | 251 (3.3) | 203 (3.8) |
| Ever hypertensive disorder of pregnancy | 328 (4.3) | 285 (5.3) |
| Ever low birth weight offspring (< 2500 g) | 624 (8.3) | 373 (7.0) |
| First CVD event during 10 years of follow-up | 257 (3.4) | 405 (7.6) |
| Myocardial infarction | 101 (1.3) | 149 (2.8) |
| Angina | 67 (0.9) | 93 (1.7) |
| Stroke | 72 (1.0) | 125 (2.3) |
| TIA | 22 (0.3) | 46 (0.9) |
Presented as n (%) unless otherwise noted
CVD cardiovascular disease, IQR interquartile range, TIA transient ischemic attack
a ± 0.5 years
bA subset of participants attended clinical visits at both age 50 and 60 years
cn = 5666 participants (75.0%) with hypercholesterolemia (≥ 5.0 mmol/l) and 37 (0.5%) with lipid lowering medication at age 50 years
dn = 4488 participants (83.7%) with hypercholesterolemia (≥ 5.0 mmol/l) and 167 (3%) with lipid lowering medication at age 60 years