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. 2018 Jul 30;33(10):1003–1010. doi: 10.1007/s10654-018-0429-1

Table 1.

Baseline characteristics of study sample and first CVD event during 10-year follow-up by age at clinical assessment (n = 11110)

Characteristic Age 50a Age 60a
Number of participants 7552 (68.0%)b 5360 (48.2%)b
Systolic blood pressure, mmHg, median (IQR) 125 (115, 140) 136 (122, 150)
Total serum cholesterol, mmol/L, median (IQR) 5.64 (5.00, 6.38)c 5.96 (5.29, 6.70)d
Anti-hypertensive medication 811 (10.7) 1214 (22.7)
Current smoker 1851 (24.5) 1007 (18.8)
Diabetes mellitus 66 (0.9) 138 (2.6)
Body mass index, kg/m2, median (IQR) 24.7 (22.7, 27.6) 25.9 (23.5, 28.9)
Parity
 1 2926 (38.7) 1678 (31.3)
 2 3394 (44.9) 2646 (49.4%)
 3 981 (13.0) 833 (15.5)
 ≥ 4 251 (3.3) 203 (3.8)
Ever hypertensive disorder of pregnancy 328 (4.3) 285 (5.3)
Ever low birth weight offspring (< 2500 g) 624 (8.3) 373 (7.0)
First CVD event during 10 years of follow-up 257 (3.4) 405 (7.6)
 Myocardial infarction 101 (1.3) 149 (2.8)
 Angina 67 (0.9) 93 (1.7)
 Stroke 72 (1.0) 125 (2.3)
 TIA 22 (0.3) 46 (0.9)

Presented as n (%) unless otherwise noted

CVD cardiovascular disease, IQR interquartile range, TIA transient ischemic attack

a ± 0.5 years

bA subset of participants attended clinical visits at both age 50 and 60 years

cn = 5666 participants (75.0%) with hypercholesterolemia (≥ 5.0 mmol/l) and 37 (0.5%) with lipid lowering medication at age 50 years

dn = 4488 participants (83.7%) with hypercholesterolemia (≥ 5.0 mmol/l) and 167 (3%) with lipid lowering medication at age 60 years