Fig. 1.

Chaos and clues in melanoma. a Asymmetry of structure and color (“chaos”); clues to malignancy: eccentric structureless zone, gray dots, on the left side, black dots in the periphery, thick reticular lines. Histopathologic diagnosis: melanoma. b Asymmetry of structure and color (“chaos”); clues to malignancy: eccentric gray and blue structureless zone, black dots in the periphery, segmental radial lines at the periphery, white lines. Histopathologic diagnosis: melanoma. Images courtesy of the Vienna Dermatologic Imaging Research Group, Department of Dermatology, Medical University of Vienna, Austria.