Table 2.
Overview of included articles studying males with congenital adrenal hyperplasia with measures and investigated domains
| Reference | Measures | Psych | QoL | SPRH | Summary of findings |
|---|---|---|---|---|---|
| Arlt et al. [5] | Short Form Health Survey (SF-36) Hospital Anxiety and Depression Scale (HADS) The International Index of Erectile Function Questionnaire (IIEF-5) CAH-Well-Being Questionnaire |
x | x | x | Reduced QoL Increased anxiety scores Erectile dysfunction in 41% |
| Berenbaum et al. [61] | Child Behavior Checklist (CBCL) Self-Image Questionnaire for Young Adolescents (SIQYA) Multidimensional Personality Questionnaire (MPQ) |
x | Higher on negative emotionality | ||
| Dudzinska et al. [37] | Short Form Health Survey (SF-36) Giessen Subjective Complaints List (GBB-24) Hospital Anxiety and Depression Scale (HADS) Brief Sexual Function Inventory (BSFI) |
x | x | x | Reduced QoL Higher depression and anxiety scores Some sexual problems |
| Falhammar et al. [59] | Psychiatric diagnoses according to ICD-8, -9, and -10 | x | Increase of psychological disorders and alcohol misuse | ||
| Falhammar, Nyström, and Thorén [29] | McCoy modified Psychological Well-being Index (PGWB) |
x | x | Sexual satisfaction and QoL similar to controls Less sexually active |
|
| Gilban et al. [54] | Child Health Questionnaire - Parent Form (CHQ-PF50) Pediatric Quality of Life Inventory (PedsQoL 4.0) |
x | Impairment of HRQoL | ||
| Idris et al. [58] | Child Behavior Checklist (CBCL) | x | Adverse psychological adjustment | ||
| Jacobs et al. [56] | Tension Scales of the Profile of Mood States (POMS) | x | Adrenal suppressive therapy effective on anxiety disorders | ||
| Mueller et al. [36] | Schedule for Affective Disorders and Schizophrenia for School Aged Children (KSADS-PL) | x | Increased rates of anxiety disorders & disruptive behavioral disorders | ||
| Reisch et al. [60] | Short Form Health Survey (SF-36) Giessen Subjective Complaints List (GBB-24) Hospital Anxiety and Depression Scale (HADS) |
x | Mildly impaired QoL | ||
| Strandquist et al. [57] | Proxies for QOL | x | QoL parameters differed significantly from matched controls |
Psych psychological and psychiatric, QoL quality of life, SPRH self-perceptions of reproductive health