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Percentage of patients reporting treatment-related adverse events related to study drug: a in the different treatment groups: placebo, HDM-DBPC, and HDM-All. b Distribution according to local, systemic and serious adverse event (AE). (DBPC Phase: placebo n = 221, HDM DBPC n = 214; HDM-All n = 279). HDM-DBPC high-dose HDM allergoid AIT double-blind placebo controlled, HDM-RCT(UC) high-dose HDM allergoid AIT usual care controlled, HDM-ALL HDM-DBPC plus HDM-RCT(UC), AE adverse event
