FIG 2.

Benznidazole treatment in both the acute and chronic stage cures BALB/c mice infected with T. cruzi strain CL Brener. (A) Outline of infection and treatment schedule. Mice were treated with 100 mg/kg benznidazole once daily by the oral route for 20 days (see Materials and Methods). (B) Representative ventral in vivo images of treated (starting day 14, 66, or 110) and nontreated mice at sequential time points postinfection. (C) Ex vivo bioluminescence images of organs and tissues taken at 169 days postinfection (dpi). Organs arranged as shown in Fig. 1C.