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Phenotypic analysis results for patients who experienced virologic breakthrough at week 96 while adherent to the study drug
| Parameter | TAF | TDF |
|---|---|---|
| No. of patients phenotyped (% of patients sequenced) | 18 (19) | 7 (15) |
| Virologic breakthrough without nonadherence | 13 | 7 |
| Conserved site changes | 5 | 0 |
| Mean EC50 fold change from baseline | 1.03 | 0.94 |
| Range of fold change from baseline | 0.39–1.51 | 0.63–1.69 |
