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(A) Mass spectrometry of AmpC1 apoenzyme after 15 min (shaded) and 24 h (nonshaded) of incubation. Shown is mass spectrometry of the AmpC1-avibactam acyl-enzyme complex after 15 min and 24 h of incubation at 1:1 and 1:10 enzyme/avibactam ratios. (B) Summary of mass spectrometry data, including description of peaks formed.
