TABLE 2.

Comparison of APX001A MICs (mg/liter) to those for other licensed antifungal agents for contemporary Danish bloodstream isolates and C. auris

Species	APX001A			AMB			ANF			MFG			FLC			VRC
	MIC range	Modal MIC	% > ECOFF	MIC range	Modal MIC	% > ECOFF	MIC range	Modal MIC	% > ECOFF	MIC range	Modal MIC	% > ECOFF	MIC range	Modal MIC	% > ECOFF	MIC range	Modal MIC	% > ECOFF
Danish blood isolates
C. albicans	0.001–0.03	0.008	0	0.06–0.5	0.25	0	≤0.004–0.016	< = 0.004	0	≤0.004–0.03	0.008	1.8	0.03–4	0.25	0.5	≤0.004–0.06	≤0.004	0.5
C. dubliniensis	0.002–0.03	0.004	3.4	0.03–0.125	0.06	0	≤0.004–0.016	0.008	0	≤0.004–0.03	0.016	ND	0.06–32	0.125	3.4	≤0.004–0.125	0.008	3.4
C. glabrata	0.008–0.25	0.06	1	0.06–0.5	0.5	0	0.008–0.25	0.016	1.1	≤0.004–0.125	0.016	2.2	0.5–>32	4	9.5	0.016–>4	0.06	9.5
C. krusei	0.5–>0.5	>0.5	NDa	0.5–1	1	0	0.016–0.06	0.03	0	0.06–0.5	0.125	3.2	8–>32	32	ND	0.125–2	0.25	ND
C. parapsilosis	0.008–0.03	0.03	0	0.25–1	0.5	0	0.5–2	0.5	0	0.5–2	2	0	0.5–2	0.5/1	0	0.008–0.03	0.016	0
C. tropicalis	0.004–0.125	0.008	3.4	0.25–0.5	0.5	0	≤0.004–0.03	0.016	0	≤0.004–0.06	0.03	0	0.25–32	0.25/0.5	15.2	0.008–>4	0.016	18.2
Other Candida spp.	≤0.0005–>0.5	0.008	ND	0.125–1	0.25	ND	≤0.004–2	0.03	ND	0.016–0.5	0.06	ND	0.125–32	0.5	ND	0.008–0.25	0.008	ND
Other yeast spp.	0.3–0.5	0.25	ND	0.25–1	0.25	ND	0.06–>4	>4	ND	0.125–>4	>4	ND	2–16	16	ND	0.016–0.5	0.125	ND
Indian clinical isolate
Candida auris	0.001–0.125	0.016	0	0.5–1	1	0	1–>32	0.06	8.2	0.03–>32	0.125	6.6%	1–>256	>256	ND	0.004–4	1	ND

^aND, not done.