TABLE 1.
Comparison of percentages of drug remaining in the mixing chamber during the adsorption experiment by initial drug concentration or blood flow rate
| Initial concn (mg/liter) | Blood flow rate (ml/min) | % drug remaining at 3 h (mean ± SD) |
|
|---|---|---|---|
| Meropenem | Vaborbactam | ||
| 50 | 200 | 89 ± 13 | 91 ± 5 |
| 100 | 85 ± 9 | 95 ± 7 | |
| 5 | 200 | 83 ± 10 | 96 ± 6 |
| 100 | 102 (n = 1)a | 98 (n = 1)a | |
a
For all results, the experiments was repeated three times except for the 5-mg/liter initial concentration with blood flow rate of 100 ml/min, for which the experiment was performed only once.