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Effect of point of dilution on meropenem-vaborbactam sieving coefficients of the AN69 ST150 filter at a blood flow rate of 200 ml/min and different effluent flow rates
| Effluent flow rate (liters/h) | Sieving coefficient by drug and point of dilution (mean ± SD) |
|||
|---|---|---|---|---|
| Meropenem |
Vaborbactam |
|||
| Prefilter | Postfilter | Prefilter | Postfilter | |
| 4 | 1.28 ± 0.14 | 1.18 ± 0.09 | 0.80 ± 0.16 | 0.78 ± 0.18 |
| 2 | 1.16 ± 0.09 | 1.53 ± 0.28 | 0.85 ± 0.15 | 1.04 ± 0.28 |
| 1 | 1.13 ± 0.01 | 1.18 ± 0.06 | 0.82 ± 0.24 | 0.80 ± 0.15 |
