TABLE 2.
Calculated IC50s of ebselen for inhibition of planktonic growth and inhibition of biofilm formation for representative strains of other Candida species
| Candida species | IC50 (μg/ml [95% CIa]) |
|
|---|---|---|
| Planktonic | Biofilm | |
| C. albicans | 2.832 (2.634–3.044) | 8.967 (≤9.514) |
| C. dubliniensis | 0.4012 (0.3728–0.431) | 5.01 (3.514–7.282) |
| C. tropicalis | 0.6979 (0.5217–0.9181) | 10.35 (≤11.4) |
| C. parapsilosis | 0.9341 (0.8296–1.047) | 4.296 (3.106–5.891) |
| C. glabrata | 0.537 (undetermined) | 4.705 (undetermined) |
| C. lusitaniae | 0.2913 (≤0.3043) | 6.867 (undetermined) |
| C. krusei | 1.421 (1.298–1.548) | 2.843 (2.419–3.325) |
a
CI, confidence interval.