TABLE 3.

MIC values of ebselen and current antifungals against multiple clinical isolates belonging to different fungal species for determination of antifungal action

Species	MIC (μg/ml)
	50%			100%
	FLC	CSP	Ebselen	Ebselen	VOR	POS
C. parapsilosisa	0.5		0.5	4
C. kruseia	16		1	4
Paecilomyces variotiia			4	8		0.125
C. albicans	<0.125		2	4
	<0.125		2	4
	>64		2	2
C. glabrata		1	1	4
		0.25	0.5	1
		0.25	1	2
Cryptococcus neoformans	8		4	4
	32		2	2
	32		1	2
Rhizopus arrhizus			8	16		0.5
			8	16		0.25
Aspergillus fumigatus			4	4	0.5
			4	4	2
			4	4	0.25
Fusarium oxysporum			4	4	4
			4	4	4
Fusarium solani			4	8	>16
Scedosporium apiospermum			8	8	2
			2	8	1
Lomentospora prolificans			4	>32	>16
			4	>32	>16
			2	8	>16

^aQuality control strains.